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Introduction by the column editor: In this issue Psychiatric Services introduces a new quarterly column that will highlight and explore the role of multimedia in the development and application of psychiatric services to a spectrum of populations in a variety of therapeutic settings. Far from being technologically oriented, the column's goal is to provide information on the very human and healing effects that modern information technology can achieve when creative and novel methods are used to enhance research, clinical practice, and training in our biopsychosocial field. This initial column highlights these goals by examining current and rapidly developing research on and clinical applications of virtual reality technology.