Preventing Poor Vocational Functioning in Psychosis Through Early Intervention
Abstract
Objective:
This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development.
Methods:
Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis.
Results:
Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area.
Conclusions:
Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.