2002–2007: Five Years of Dramatic Change in Antipsychotic Prescribing
With a choice of more than 90 antipsychotic products, physicians who regularly prescribe antipsychotics often rely heavily on a few drugs per class. Nevertheless, this analysis of 2002–2007 prescribing data for nearly 7,400 U.S. physicians found dramatic changes in preferences for eight antipsychotics. Physicians’ reliance on a preferred agent declined over the period, particularly among psychiatrists. The authors discuss an array of factors that may have affected prescribing practices during this period, including research calling into question the superiority of second-generation antipsychotics and FDA warnings of troublesome side-effect profiles.