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Published Online:https://doi.org/10.1176/appi.ps.202100197

Abstract

Objective:

Among veterans with posttraumatic stress disorder (PTSD), supported employment that utilizes the individual placement and support (IPS) model has resulted in consistently better employment and functional outcomes than usual vocational rehabilitation services. This study aimed to compare these two approaches in terms of health services use and associated costs.

Methods:

A secondary analysis of a multisite randomized controlled trial of 541 unemployed veterans with PTSD used archival data from electronic medical records to assess the use and costs of health services of IPS and usual care (i.e., a transitional work [TW] program) over 18 months. Comparisons were also made to an 18-month postintervention period.

Results:

The two study groups did not differ in number of inpatient days or in utilization or cost of high-intensity services. Annual per-person costs of health services were approximately 20% higher for IPS than for TW participants (mean difference=$4,910 per person per year, p<0.05) during the intervention period, largely driven by higher utilization and costs for vocational services in the IPS group (p<0.001). These costs declined postintervention to nonsignificant differences. The mean annual per-person vocational service cost was $6,388 for IPS and $2,549 for TW (mean difference=$3,839, p<0.001) during the intervention period.

Conclusions:

In keeping with IPS’s intensive case management approach, veterans receiving IPS used more vocational services and had correspondingly higher costs than veterans receiving TW. The two groups did not differ in use or cost of other types of health services. Future research should examine whether higher short-term costs associated with IPS relative to usual care result in long-term cost savings or higher quality of life for persons with PTSD.

HIGHLIGHTS

  • Annual per-person costs for health services were 20% higher for unemployed veterans receiving individual placement and support (IPS) than for those receiving usual care (i.e., a transitional work [TW] program).

  • Participants receiving IPS used more vocational services and incurred higher costs from vocational services than did those receiving usual care.

  • The mean annual per-person cost for IPS services for veterans diagnosed as having PTSD was well within the range of IPS costs reported in other populations.

  • IPS and TW did not differ in utilization or costs of inpatient services, emergency department or urgent care, or nonvocational outpatient services.

Numerous studies have demonstrated the effectiveness of supported employment that utilizes the individual placement and support (IPS) model (1, 2). IPS focuses on a rapid job search in a competitive work setting and individualized follow-up support to ensure job sustainment and successful transition. An IPS specialist works with a mental health treatment team to share in treatment decisions, discuss the client’s employment status, and maximize clinical recovery plans, thereby providing the client with integrated support in vocational and clinical domains (3). According to a meta-analysis of randomized controlled trials (RCTs), people receiving IPS services were 2.4 times more likely to be employed than those receiving traditional vocational services (4, 5). Although most studies of IPS’s effectiveness have focused on populations with serious mental illness (i.e., schizophrenia, bipolar disorder, or major depression), rigorous studies have also shown the effectiveness of IPS for veterans with posttraumatic stress disorder (PTSD). A Veterans Health Administration (VHA) multisite RCT found that unemployed veterans with PTSD who received IPS were twice as likely to attain steady employment and had significantly higher cumulative earnings from competitive jobs compared with those who received usual care in the form of a transitional work (TW) program (6).

PTSD has profound effects on occupational functioning and is associated with increased unemployment rates (710). It may also substantially affect health care utilization. In a sample of primary care patients in an urban area, patients with a PTSD diagnosis had more hospitalizations, inpatient days, and mental health visits than patients without this diagnosis (11). In a study examining VHA health utilization data, patients with comorbid depression and PTSD incurred more frequent mental health visits, more outpatient visits overall, greater use of antidepressant medications, and higher costs for mental health care compared with patients with depression but without PTSD (12).

Employment is an essential component of recovery for people with a serious mental illness (13), and evidence suggests that it may be associated with lower use and costs of health services (14, 15). IPS has been shown to be cost-effective and to lead to less inpatient and outpatient utilization and lower costs compared with usual care vocational services (1622). These findings may be the result of greater improvements in psychosocial functioning and life satisfaction among IPS clients (23) due to the integrated treatment approach of IPS or to the direct benefits of the work itself. Whether IPS could confer a similar benefit on the use and costs of health services incurred by veterans with PTSD remains unexplored.

In this article, we describe the utilization and costs of health services in a cohort of unemployed veterans diagnosed as having PTSD who participated in the aforementioned VHA RCT comparing IPS with TW (6). This post hoc secondary analysis tested three a priori hypotheses: compared with those enrolled in usual care (i.e., TW), veterans receiving IPS would accrue significantly fewer inpatient days, have lower total costs for high-intensity services (e.g., hospitalizations and emergency department [ED] or urgent care visits), and have higher total costs for health care services. Additionally, utilization and costs during the 18-month intervention period were compared with an 18-month postintervention period. Finally, a breakdown of the use and cost of vocational services was examined.

Methods

The parent VIP-STAR (Veterans Individual Placement and Support Toward Advancing Recovery) study was a multisite RCT that compared the effectiveness of IPS (N=271 patients) and TW (N=270 patients). The inclusion criteria were U.S. military veterans ages ≤65 years, lifetime diagnosis of PTSD, current unemployment, eligibility for usual care vocational services, interest in competitive employment, and residence in the catchment area of one of the participating study sites. Individuals were excluded if they had received a diagnosis of schizophrenia, schizoaffective, or bipolar I disorder; were in immediate need of detoxification or inpatient care; or were suicidal or homicidal. Veterans across 12 study sites who provided informed consent and met eligibility criteria were randomly assigned to either IPS or TW. Their work status, PTSD symptoms, and functioning were assessed during the 18-month study period. The TW services offered veterans temporary work assignments, predominantly in minimum-wage, entry-level jobs within the VHA facility, on the premise that these employment experiences would help prepare them for competitive work. In contrast, IPS included a rapid search for a competitive, well-matched community-based job and individualized support from an IPS specialist who collaborated with the PTSD treatment team. In keeping with the practices of IPS and usual care, IPS services continued for the entire 18-month study period, regardless of whether the veteran obtained a competitive job, whereas the TW services ended soon after the veteran obtained a competitive job. All participants given a random assignment in the parent study were included in the analyses for the present health services study. This study was approved by the Birmingham, Hines, and Tuscaloosa U.S. Department of Veterans Affairs (VA) institutional review boards.

Sources and Measures of Cost Data

We linked the multisite study data with health services utilization and cost data from the VHA Corporate Data Warehouse by using VINCI (the VHA Informatics and Computing Infrastructure). All VHA utilization data, including on general medical and psychiatric hospitalizations, domiciliary or residential care, ED or urgent care visits, medical and mental health outpatient visits, vocational rehabilitation and housing services, ancillary (e.g., chaplaincy and bereavement counseling) and administrative services, and outpatient medications, were obtained from national VHA databases, which capture utilization from electronic medical records at local VHA facilities (24, 25). The direct costs of IPS, TW, and other VHA-based health services utilization were obtained from the VA Managerial Cost Accounting (MCA) National Data Extracts (NDEs) (26). MCA draws information from the VA’s accounting and payroll system and combines these data with workload information to produce cost estimates. Each IPS or TW service that a veteran receives has a unique clinic stop code (568 for IPS and 574 for TW). Consequently, the cost data in the MCA NDEs were used to estimate the costs of the intervention and costs associated with all other VHA services utilized. Costs of prescriptions from VHA pharmacies were based on the VHA’s acquisition and dispensing costs (27).

Analytic Methods

We aggregated the cost data into 11 categories: general medical hospitalizations, psychiatric hospitalizations, domiciliary or residential stays, ED or urgent care visits, outpatient medical encounters, outpatient mental health encounters, pharmacy, vocational rehabilitation services (which include IPS and TW), housing services, ancillary services, and administrative services (e.g., prescription processing). We then added all costs to calculate total costs for the 18-month intervention and 18-month postintervention periods. Annual per-person costs for each cost category were calculated separately for IPS and TW participants and were assessed by using summary statistics. Costs were annualized and standardized to 2019 U.S. dollars. We used t tests to compare the mean annual per-person cost of IPS and TW for each cost category during the intervention and postintervention periods. We used chi-square tests to compare the number of users of each health service type between groups. We also used t tests to compare differences in the mean number of encounters between groups. All analyses were conducted with R, version 4.0.0 (28).

Results

Baseline Characteristics

The IPS and TW groups did not significantly differ in demographic or clinical characteristics at baseline (Table 1). Of all study participants (N=541), 82% (N=442) were men, 51% (N=274) were White, 42% (N=225) Black, 17% (N=90) Latinx, 13% (N=68) other races, and 82% (N=444) had more than a high school education. The mean±SD age was 42.1±10.9 years. Two-thirds of the sample (N=356) had experienced a past major depressive episode, and nearly one-third (N=170) were experiencing a major depressive episode at baseline. Mean PTSD duration was 13.3±11.4 years. Other sample characteristics not used in this analysis are reported elsewhere (6).

TABLE 1. Baseline characteristics of veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW)a

IPS (N=271)TW (N=270)
CharacteristicN%N%
Sex
 Male2248321881
 Female47175219
Race-ethnicityb
 White1385113650
 Black1154211041
 Other race32123613
 Latinx43164717
Marital status
 Never married68256725
 Married89338431
 Divorced82307929
Education
 Less than college54204316
 College credit or degree2017421078
 Postgraduate credit or degree166176
Comorbid mental health conditionc
 Current major depressive episode87328331
 Past major depressive episode1836817364
 Agoraphobia64245922
 Panic disorder37146624
 Social anxiety disorder35132810
 Past-year alcohol use disorder54207829
Age (M±SD years)42.5±10.741.9±11.2
PTSD duration (M±SD years)13.3±11.613.4±11.3

aDenominators for some characteristics vary because of missing data. No significant between-group differences were found.

bParticipants could indicate more than one racial group.

cParticipants could have more than one comorbid mental health condition.

TABLE 1. Baseline characteristics of veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW)a

Enlarge table

Utilization, Inpatient Days, and Cost of High-Intensity Services

The two groups did not significantly differ in the mean number of inpatient days for psychiatric (IPS, 0.9±4.2; TW, 0.8±2.9) or general medical hospitalizations (IPS, 0.7±2.6; TW, 0.6±2.4) during the 18-month intervention period. The two groups also did not differ in ED or urgent care visits, general medical hospitalizations, or psychiatric hospitalizations (Table 2). More than 60% of the study participants had an ED or urgent care visit, 12% had a medical hospitalization, and 11% had a psychiatric hospitalization during the intervention period (Table 2). During the postintervention period, 9% of participants had a general medical hospitalization, 4% had a psychiatric hospitalization, and 38% had ED or urgent care use (Table 3). There were no significant differences in costs for other categories of high-intensity services (ED or urgent care, general medical hospitalization, or psychiatric hospitalization) between the groups during the intervention or postintervention period (Tables 4 and 5).

TABLE 2. Use of health services and health care encounters among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW) during the 18-month intervention perioda

Users of health servicesbHealth care encounters
IPS (N=271)TW (N=270)IPS (N=271)TW (N=270)IPS vs. TW
Service typeN%N%MSDMSDMean difference95% CI
Vocational rehabilitation248922489230.925.313.614.317.3**13.8 to 20.8
General medical hospitalization35133112.21.73.17.66.04−.08 to .2
Psychiatric hospitalization26103112.201.0.14.45.06−.07 to .2
Domiciliary or residential care197207.10.41.09.33.01−.05 to .07
ED or urgent care16360174641.82.81.92.8−.1−.6 to .4
Outpatient medical care265982679932.232.235.731.5−3.5−8.9 to 1.9
Outpatient mental health care268992679941.649.139.642.52.0−5.7 to 9.7
Pharmacy262972659852.153.160.662.4−8.5−18.2 to 1.3
Housing services9134101376.415.97.215.6−.8−3.5 to 1.8
Ancillary services39145320.41.9.82.8−.4−.8 to .02
Administrative services18468204762.73.53.43.5−.7*−1.3 to −.1

aED, emergency department.

bChi-square tests were nonsignificant.

*p<0.05, **p<0.001.

TABLE 2. Use of health services and health care encounters among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW) during the 18-month intervention perioda

Enlarge table

TABLE 3. Use of health services and health care encounters among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW) in the 18-month postintervention perioda

Users of health servicesbHealth care encounters
IPS
(N=271)
TW
(N=270)
IPS
(N=271)
TW
(N=270)
IPS vs. TW
Service typeN%N%MSDMSDMean difference95% CI
Vocational rehabilitation1455459223.16.31.14.62.0**1.1 to 2.9
General medical hospitalization249249.14.58.13.50.01−.08 to .1
Psychiatric hospitalization114104.08.43.07.38.01−.06 to .08
Domiciliary or residential care124124.06.30.06.31.0−.05 to .05
ED or urgent care10338101371.01.9.91.5.1−.2 to .4
Outpatient medical care240892449017.921.017.719.3.3−3.2 to 3.7
Outpatient mental health care220812248314.227.815.030.3−.8−5.7 to 4.2
Pharmacy237872479228.034.132.338.9−4.4−10.5 to 1.8
Housing services552068252.68.22.98.2−.3−1.7 to 1.1
Ancillary services2182710.31.5.31.3.0−.2 to .3
Administrative services12847154571.83.61.82.5.0−.5 to .6

aED, emergency department.

bChi-square tests were nonsignificant.

**p<0.001.

TABLE 3. Use of health services and health care encounters among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW) in the 18-month postintervention perioda

Enlarge table

TABLE 4. Mean unadjusted annual per-person costs for health services in the 18-month intervention period among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW)a

IPS (N=271)TW (N=270)IPS vs. TW
Service typeM95% CIMedianIQRM95% CIMedianIQRMean difference95% CI
Vocational rehabilitation6,3885,512–7,2644,8549,6962,5492,148–2,9501,4793,2133,839**2,874 to 4,803
General medical hospitalization2,5961,481–3,710002,0691,102–3,03600526−950 to 2,003
Psychiatric hospitalization1,687733–2,641001,498870–2,12600189−954 to 1,332
Domiciliary or residential care2,163890–3,437001,9381,019–2,85700225−1,346 to 1,796
ED or urgent care889727–1,0514561,236934766–1,1024751,245−45−278 to 189
Outpatient medical care6,1005,326–6,8753,8396,7816,5425,661–7,4244,4005,795−442−1,615 to 731
Outpatient mental health care6,9766,031–7,9224,1697,3206,3215,573–7,0694,3426,170655−551 to 1,862
Pharmacy1,325889–1,7612608931,291783–1,79931881933−636 to 703
Housing services1,295884–1,70504761,282939–1,626070913−523 to 548
Ancillary services379–66005824–9200−20−65 to 24
Administrative services234176–29165224298246–349109421−64−141 to 13
Total29,69126,427–32,95520,68324,80324,78122,002–27,56017,18822,9494,910*622 to 9,198

aAll values are in US$. ED, emergency department; IQR, interquartile range.

*p<0.05, **p<0.001.

TABLE 4. Mean unadjusted annual per-person costs for health services in the 18-month intervention period among veterans with PTSD receiving individual placement and support (IPS) or transitional work (TW)a

Enlarge table

Total Cost and Utilization of Health Services

As hypothesized, the overall costs of health services utilization were higher for veterans in the IPS group than for those in the TW group during the 18-month intervention period (Table 4). Unadjusted annual mean costs per person were $29,691 (95% confidence interval [CI]=$26,427–$32,955) for the IPS group and $24,781 (95% CI=$22,002–$27,560) for the TW group, a difference of $4,910 (95% CI=$622–$9,198), or a 19.8% higher annual cost for IPS participants compared with TW participants. These cost differences were driven by significantly higher utilization of vocational services in the IPS group compared with the TW group, as detailed below. Outpatient medical and nonvocational mental health utilization and costs were not significantly different between the two groups during the intervention period (Tables 2 and 4). More than 96% (N=520) of participants had at least one mental health outpatient visit, general medical outpatient visit, and prescription filled.

During the postintervention period, the IPS and TW groups did not significantly differ in outpatient service use, outpatient service costs, or overall costs (Tables 3 and 5). Unadjusted annual mean costs per person were $20,821 (95% CI=$16,143–$25,499) for the IPS group and $18,292 (95% CI=$14,826–$21,757) for the TW group, a difference of $2,530 (95% CI=−$3,295 to $8,354). Outpatient general medical costs (IPS, mean=$5,884, 95% CI=$4,823–$6,945; TW, mean=$5,397, 95% CI=$4,517–$6,277) and outpatient mental health costs (IPS, mean=$3,383, 95% CI=$2,738–$4,028; TW, mean=$3,652, 95% CI=$2,835–$4,468) were the largest cost categories.

TABLE 5. Mean unadjusted annual per-person costs for health services in the 18-month postintervention period among veterans with PTSD who received individual placement and support (IPS) or transitional work (TW)a

IPS (N=271)TW (N=270)IPS vs. TW
Service typeM95% CIMedianIQRM95% CIMedianIQRMean difference95% CI
Vocational rehabilitation966756–1,17601,293385203–56700581**303 to 858
General medical inpatient care3,3971,268–5,526002,754946–4,56200643−2,151 to 3,437
Psychiatric inpatient care1,182220–2,14300915253–1,57700266−902 to 1,435
Domiciliary or residential care2,823620–5,026001,708509–2,907001,115−1,396 to 3,626
ED or urgent care687523–8510782631500–763078056−155 to 266
Outpatient medical care5,8844,823–6,9452,3125,9195,3974,517–6,2772,8975,652487−892 to 1,866
Outpatient mental health care3,3832,738–4,0281,5233,6043,6522,835–4,4681,8723,590−269−1,309 to 771
Pharmacy1,100668–1,5321404581,352437–2,267197640−252−1,263 to 758
Housing services943568–1,319001,072688–1,45600−129−666 to 408
Ancillary services3812–64004311–7500−5−47 to 36
Administrative services419215–6220223381218–5443425337−223 to 298
Total20,82116,143–25,4998,28419,59318,29214,826–21,7578,88615,4582,530−3,295 to 8,354

aAll values are in US$. ED, emergency department; IQR, interquartile range.

**p<0.001.

TABLE 5. Mean unadjusted annual per-person costs for health services in the 18-month postintervention period among veterans with PTSD who received individual placement and support (IPS) or transitional work (TW)a

Enlarge table

In both study groups, overall costs significantly declined from the 18-month intervention period to the postintervention period. Among IPS participants, mean overall costs dropped by $8,870 (95% CI=$3,166–$14,574). Among TW participants, mean overall costs dropped by $6,490 (95% CI=$2,048–$10,932). The unadjusted difference in the decline between the two groups was not statistically significant (mean=$2,380, 95% CI=−$3,436 to $8,197).

Outpatient mental health costs also significantly declined from the 18-month intervention period to the postintervention period in both study groups. Mean outpatient mental health costs dropped by $3,594 (95% CI=$2,449–$4,738) in the IPS group and by $2,669 (95% CI=$1,562–$3,777) in the TW group. The unadjusted difference in the decline between the two groups was not statistically significant (mean=$924, 95% CI=−$123 to $1,972).

Utilization and Costs of Vocational Services

During the 18-month intervention period, IPS participants had a mean of 30.9 vocational service encounters, which was more than twice as many encounters as for TW participants (mean=13.6, p<0.001) (Table 2). On the basis of our a priori consensus definition of clinically meaningful engagement in services, “engaged in vocational services” was defined as having at least four IPS encounters for the IPS arm and at least four TW encounters or TW income >$0 in the TW arm, because income alone would be sufficient to demonstrate TW program engagement. A significantly higher proportion of IPS users (N=222, 82%) were engaged in vocational services, compared with TW users (N=143, 53%) (χ2=52.8, p<0.001; data not shown). During the postintervention period, although vocational service use in both groups was lower during this period than during the intervention period, IPS participants were more than twice as likely as TW participants to use vocational services (54% vs. 22%, p<0.001) and had three times as many vocational service encounters (3.1 vs. 1.1, p<0.001) (Table 3).

The only significantly different cost category between the two groups during the intervention period was vocational services (Table 4): unadjusted annual mean cost per person was $6,388 (95% CI=$5,512–$7,264) for the IPS group and $2,549 (95% CI=$2,148–$2,950) for the TW group, a difference of $3,839 (95% CI=$2,874–$4,803). Although substantially lower than during the intervention period, mean costs of postintervention vocational services (Table 5) were still significantly higher in the IPS group ($966, 95% CI=$756–$1,176) than in the TW group ($385, 95% CI=$203–$567). The IPS group had a significantly greater reduction in vocational service costs from the intervention period to the postintervention period compared with the TW group (mean difference=$3,258, 95% CI=$2,351–$4,165).

Discussion

Among veterans with a diagnosis of PTSD treated in VHA settings, we found that participants receiving IPS incurred about $4,900 more in overall annual health care costs per person during the intervention period (∼20% higher) than participants receiving usual care (TW), which declined to a nonsignificant mean difference of $2,530 annually per person in the postintervention period. This cost difference was due to the greater use of vocational services among those in the IPS group and the corresponding cost (mean difference=$3,839 per person annually). Previous research has found that use of these services leads to a significantly greater number of weeks worked among IPS recipients compared with control groups (29). The magnitude of vocational services use among the IPS participants in our study (mean=30.9 encounters per year) was consistent with the number of IPS contacts in a non-VHA research study that reported a strong association between IPS service intensity and better employment outcomes (29). During the intervention period, IPS participants were significantly more likely than TW participants to engage in vocational services (82% vs. 53%, respectively). Although vocational service encounters decreased for both groups during the postintervention period, IPS participants remained more likely than those receiving TW to use vocational services.

The 2019 annual cost of IPS vocational services estimated from VHA MCA data in our study—$6,388 per person per year—falls within the range estimated in earlier reports ($4,000–$8,000 per person per year) by investigators in non-VHA settings (30). A simple calculation of the average cost of an IPS specialist in 2013 divided by the program’s low client caseload of 14 patients per specialist yielded an estimate of $5,100 per client per year (30). It is worth noting that the cost of IPS is highest during the first 12 months of service and declines as the intensity of IPS services diminishes over time. It is important to limit IPS specialists’ caseloads to 25 clients, because higher caseloads can reduce IPS fidelity and negatively affect employment outcomes.

In a separate analysis, we also evaluated the cost-effectiveness and return on investment of these interventions by using these data (31). Similar to the findings of Dixon et al. (32), Hoffmann et al. (16), and Zheng et al. (33), we found that IPS was more cost-effective and provided a better return on investment than TW. In addition, we found that when TW income (a cost typically incurred by the VHA facilities) was included in the total health care costs, total annual costs per patient for IPS and TW were very similar ($29,828 vs. $26,772, respectively, p=0.17), thus neutralizing the cost differences that were due to IPS participants’ greater use of vocational services.

This study did not find between-group differences in the number of inpatient days or use or costs of high-intensity services. This finding differs from those of studies with people diagnosed as having serious mental illness (1618), which reported that IPS reduces the number of psychiatric hospitalizations, inpatient days, and ED visits compared with usual care vocational services. Among VHA patients who incur the greatest costs, those with a serious mental illness have higher adjusted rates of mental health services utilization (including almost twice as many hospitalizations, inpatient days, and ED visits) and a greater proportion of costs from mental health care compared with veterans with PTSD (34). Studies of populations with serious mental illness, which have high rates of high-intensity service utilization, are more likely to report an impact of IPS on such utilization and associated costs compared with studies of populations with lower service utilization.

This study had several limitations. The intervention trial was conducted within VHA facilities; therefore, these results may not fully generalize to freestanding vocational services organizations, where integrated health care services may be lacking. Additionally, these findings may not generalize to persons who access vocational services with mental health conditions other than PTSD. These limitations were partially offset by several strengths, including the completeness of data on health services utilization and cost within the VHA administrative data resources and the ability to track service use over 36 months.

Although IPS was not associated with short-term cost savings related to the use of health services among persons with PTSD, the superior vocational outcomes confer a long-term benefit that can be transformative (6). Future studies could explore whether the higher short-term costs associated with IPS relative to usual care result in long-term cost savings or higher quality of life. Research that follows up with persons with PTSD who have received vocational services over a longer period is needed to confirm these hypotheses. It is also worth exploring whether employment itself is associated with a reduction in utilization or costs of mental health services.

Conclusions

Compared with TW, the IPS intervention in VHA settings incurred predictably greater overall health care costs of about $4,900 annually per person, largely driven by the greater use of vocational services inherent in the intensive case management that is fundamental to IPS. Otherwise, IPS did not notably differ from TW in costs associated with high-intensity or general outpatient services among veterans with PTSD. Similar to other more intensive psychosocial rehabilitative interventions, IPS appears to be both more effective and more costly than usual care. Considering previous reports showing that IPS is twice as effective as TW in improving employment outcomes for veterans with PTSD (6) and leads to significantly better functional outcomes (23), these cost differences are well justified.

Center of Innovation for Complex Chronic Healthcare, Hines U.S. Department of Veterans Affairs (VA) Hospital, Hines, Illinois (Jordan, Stroupe, Cao); Department of Psychiatry and Behavioral Sciences and Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago (Jordan); Department of Public Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, Illinois (Stroupe); Center for Healthcare Organization and Implementation Research, VA Boston Healthcare System, and Boston University School of Public Health, Boston (Pogoda); Birmingham VA Research Service (Richman), Birmingham VA Medical Center, Birmingham, Alabama (Kertesz); Department of Surgery (Richman), Department of Medicine (Kertesz), and Department of Psychiatry and Behavioral Neurobiology (Davis), University of Alabama School of Medicine, Birmingham; VA West Haven Cooperative Studies Program Coordinating Center, VA Connecticut Healthcare System, West Haven, Connecticut (Kyriakides); Westat, Lebanon, New Hampshire (Bond); Research Service, Tuscaloosa VA Medical Center, Tuscaloosa, Alabama (Davis).
Send correspondence to Dr. Jordan ().

This study was funded by the VA Health Services Research and Development Service (eRA grant I01 HX-002082-01; VA Project ID IIR 15-342).

Dr. Kertesz reports personal stock ownership in Zimmer Biomet Holdings, Thermo Fisher Scientific, and Dow; royalty income based on contributions to UpToDate medical reference software; and past ownership of stock in CVS/Caremark in the year 2020. Dr. Davis reports receipt of consulting fees from Boehringer Ingelheim, Janssen, Lundbeck, Otsuka, and Signant Health and research funding or materials from Alkermes, Aptinyx, Avanir, Social Finance, Tonix, and Westat. The other authors report no financial relationships with commercial interests.

The authors acknowledge the support of the VA West Haven Cooperative Studies Program Coordinating Center and technical assistance provided by Teddy Bishop and Judy Burt at the Tuscaloosa VA Medical Center. Opinions herein are those of the individual authors, and the contents of this article do not represent the views of the VA or the United States government.

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