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October 01, 2012
Depression and Dysthymia
Expires December 31, 2014
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CME Activity

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Sample questions:
1.
It appears that peripheral cytokines enter or communicate with the CNS through which of the following mechanisms:

See Soskin and Fava: Peripheral cytokine signals can access the brain, p 145
2.
Pre-treatment with the antidepressant paroxetine, in patients receiving the pro-inflammatory cytokine, interferon-alpha, for hepatitis C or malignant melanoma has been shown to dramatically reduce rates of depression during cytokine therapy?

See Soskin and Fava: Interferon model, p 414
3.
Following a first episode of major depression lasting less than two years, the estimated likelihood of another episode across the lifespan is approximately which of the following:

See Shelton and Hollon, Introduction, p 434