Three articles in this issue present research findings on depression. To determine the prevalence of depression and examine behavioral risk factors, Tara W. Strine, M.P.H., and colleagues analyzed data from a 38-state telephone survey of more than 217,000 participants. They found an overall prevalence rate of current depressive symptoms of 8.7%, with state rates ranging from 5.3% to 13.7%. Cardiovascular disease, diabetes, asthma, smoking, and obesity were all significantly associated with current symptoms (page 1383). Two studies looked at the quality of depression care. Alexander S. Young, M.D., M.S.H.S., and colleagues examined 2.5-year follow-up data from a large sample of adults who had persistent depression or anxiety and found considerable problems with the care they received. Only a third reported receiving any treatment at baseline. At follow-up more than 40% reported persistent symptoms, but the researchers found only a modest increase from baseline in medication use and no increase in use of counseling (page 1391). Using 1999—2005 records from a national Veterans Health Administration database, Jeffrey A. Cully, Ph.D., and colleagues examined the adequacy of care (medication and follow-up visits) for more than 205,000 veterans with new-onset depression. Provision of adequate follow-up care was associated with a significant decrease in all-cause mortality in the year after illness onset (page 1399). In a Taking Issue commentary, Greer Sullivan, M.D., M.S.P.H., describes two gaps in care—the engagement gap and the quality gap. When a person with depression makes it across the engagement gap but not across the quality gap, she notes, the pattern of care could be described as "inappropriately complacent" (page 1367).