Stigma is the subject of two articles, an Open Forum, and a brief report. Jo C. Phelan, Ph.D., and coauthors address the question of whether attributions of a genetic cause of serious mental illness are associated with more positive orientations to professional treatment among the general public (page 382). Marjorie L. Baldwin, Ph.D., and Steven C. Marcus, Ph.D., analyzed the extent to which self-reports of job-related discrimination by persons with serious mental illness are associated with econometric measures of discrimination (page 388). Patrick Corrigan, Psy.D., and Betsy Gelb, Ph.D., in their Open Forum piece, present three case studies of programs for addressing the stigma associated with mental illness (page 393). In a brief report, Nicolas Rüsch, M.D., and colleagues describe their study of perceived legitimacy of discrimination and self-stigma among women with borderline personality disorder or social phobia in Germany and Switzerland (page 399).