As shown in F1, over this time frame weighted national estimates of the number of these annualized office-based physician visits increased 2.5-fold (p<.05), from 583,000 in 1995-1996 (95 percent confidence interval [CI]=329,000 to 837,000), to 1,462,000 in 2001-2002 (CI=994,000 to 1,930,000).