Several features of Integrated Treatment for Mood and Substance Use Disorders are excellent. Most of the chapters offer a practical, useful perspective, and several add clarity to relatively neglected but common clinical situations. The focus on interactions between mood disorders and substance use disorders is needed, not only because these interactions are so common but also because several recent books either are generic—that is, they address all disorders—or are specific to patients who have severe mental illness and a substance use disorder. Individual chapters in this book address the problem of nicotine addiction, which is often ignored in dual diagnosis programs, and the dilemma of evaluating and managing patients who are not responding to their current treatment regimens. Both nicotine addiction and treatment nonresponse are everyday clinical issues with which clinicians need practical assistance.