Descriptively, 115 out of 458 individuals with substantial depressive symptoms (25.1 percent) left employment within two years, compared with 16.5 percent (716 out of 4,341) of those without depression (t=4.09, df=530, p<.001). Because these groups also differed in other dimensions, we used multivariate logistic regression analysis to control for sex, age, race or ethnicity, marital status, education, family income, net wealth, number of years worked at the longest-held job, smoking status, number of persons in the household, and whether the respondent worked full-time or part-time at baseline. Because some persons had missing data, our sample size decreased to 4,795. We further stratified the data by sex and ran multivariate logistic regressions for women and for men. Adjusted results are shown in F1.