Mind, Body, and Medicine contains 20 chapters. The first nine chapters are discussions of somatization, doctor-patient communication, stress and the immune function, pathophysiological mechanisms, and placebo response. Chapters 10 through 16 are devoted to specific syndromes: chronic or recurrent pain, visceral pain, panic attacks, cardiovascular changes in anxiety, hyperventilation, chronic fatigue, and depression. Drug treatment, stress management, and behavioral interventions are discussed in chapters 17 through 19, and the concluding chapter is devoted to defining mind-body medicine. Although the book is addressed primarily to internists and primary care physicians, it is a useful resource for psychiatrists as well. For example, the concept of bidirectional interaction between brain and body, as elaborated in this book, can help psychiatrists in understanding patients' pain and chronic illness. Dr. Melmed takes a holistic approach that is free of the usual clichés and hence is thought-provoking. I recommend this book to psychiatrists, nurses, and social workers who work with patients who have chronic medical conditions.