Information on psychopharmacology is scattered throughout the text. A carefully researched and richly documented chapter by Willem M.A. Verhoeven and Sigfried Tuinier reviews the evidence on the efficacy of opiate antagonists, lithium, beta blockers, neuroleptics, selective serotonin reuptake inhibitors, anticonvulsants, and buspirone for self-injurious behaviors. Other authors describe general approaches to the mentally retarded patient who has schizophrenia, mood and anxiety disorders, attention-deficit hyperactivity disorder, or autism. Brief mention is made of a small number of syndromes such as Lesch-Nyhan, fragile X, Prader-Willi, and Cornelia de Lange.