Although its title may lead to disappointment for readers expecting to find guidance on clinical psychopharmacology, the book nevertheless has much to offer. Our scientific understanding of schizophrenia is developing quickly, and theories such as the dopamine hypothesis are no longer simple or preeminent. To understand the latest thinking about how conventional and novel antipsychotics work, one needs to move beyond neurotransmitters and consider molecular genetics. Those of us trained a generation ago may find this book helpful to bring us up to date. The book would be difficult to read from cover to cover, but individual chapters are well done and may be useful to students, young investigators, or practicing clinicians interested in the current scientific knowledge about schizophrenia.