In fact, many if not most of the decisions made in daily practice will never be subject to rigorous research protocols. Nor can government, institutions, managed care or professional organizations, or even a supervisor provide much more than a general structure, a disciplined attitude, an ethical framework, and fairly balanced financial and humanistic incentives. The actual practice of medicine and the allied disciplines has always been a personal, even private, individual or small-team creative activity, taking place within a limited set of relationships. This characteristic of practice is not likely to change, despite the legal and financial constraints that are currently causing a sense of despair and loss of morale.