The number of psychosocial interventions for relatives of adults with serious and persistent mental illness has increased significantly in recent years. Psychoeducational interventions combine educational and therapeutic objectives, offering didactic material about the ill relative's disorder and therapeutic strategies to enhance the family's communication and coping skills with the goal of reducing the patient's rate of relapse. The more recent development of family education differs from psychoeducation in that its primary goals are didactic and supportive rather than therapeutic. Interventions are focused on improving family members' quality of life by reducing stress and burden and only secondarily on benefiting the ill relative. The author reviews the conceptual and empirical basis of both psychoeducation and family education, discusses the distinctions between these two approaches in program structure and effectiveness, and suggests future policy, program, and research directions for family interventions.