The American Psychiatric Association (APA) has updated its Privacy Policy and Terms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.

×
ArticleNo Access

Clinical Management of Lithium-Induced Polyuria

Published Online:https://doi.org/10.1176/ps.44.5.427

A stepwise approach to clinical management of lithium-induced polyuria is suggested. Nonpharmacologic interventions such as dose reduction and change in dosage distribution should be tried first. If such measures prove inadequate, potassium supplementation may be tried. Pharmacologic intervention focuses primarily on amiloride, although amiloride-hydrochlorothiazide combinations are occasionally necessary. Finally, indomethacin is a newer resource available, and one recommended only for cases in which immediate normalization of polyuria is necessary.

Access content

To read the fulltext, please use one of the options below to sign in or purchase access.