Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
Psychiatric Uses of Lithium for Children and Adolescents
Judith A. Carroll; James W. Jefferson; John H. Greist
Psychiatric Services 1987; doi:
View Author and Article Information

Lithium Information Center, Department of Psychiatry, University of Wisconsin Center for Health Sciences, 600 Highland Avenue, Madison, Wisconsin 53792

American Psychiatric Association

text A A A
PDF of the full text article.

Clinical management, adverse effects, and response patterns of children and adolescents given lithium appear to be similar to those of adults. Although no clear set of therapeutic predictors has been established, best results are likely in patients with bipolar affective disorder who also have a family history of lithium-responsive affective disorder. Lithium may prove useful in some cases of treatment-resistant aggression, explosiveness, and hyperactivity, but it is generally regarded as an ineffective treatment for attention deficit disorder per se.For serious affective illness, most experts agree that treating children and early adolescents with lithium for longer than six months should be avoided if possible. When long-term therapy is indicated, the possibility of adverse developmental effects of lithium should be weighed against the disruptive effects of untreated illness.For very young children, lithium should be given only in extreme cases and only after consultation with a physician experienced in the use of lithium for young children. The Food and Drug Administration has not approved the labeling of lithium for use in conduct disorder or attention deficit disorder or in treating children under 12 years of age. The 1987 package insert reads: "Since information regarding the safety and effectiveness of lithium carbonate in children under 12 years of age is not available, its use in such patients is not recommended at this time." Nevertheless, in view of the many published reports of beneficial responses, lithium use may be justified in certain conditions when more conventional forms of therapy have failed.Regardless of the indication for lithium in children and adolescents, the medication should not be prescribed alone, but rather in conjunction with psychosocial interventions.

Abstract Teaser
Figures in this Article


Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).




CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Related Content
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 12.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 1.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 1.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 5.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 19.  >
Topic Collections
Psychiatric News
APA Guidelines
PubMed Articles