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Article   |    
Neuropsychiatric Manifestations of AIDS-Spectrum Disorders
Samuel Perry; Paul Jacobsen
Psychiatric Services 1986; doi:
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Department of psychiatry of Cornell University Medical College in New York City; Consultation-liaison division of New York Hospital; Payne Whitney Psychiatric Clinic, 525 East 68th Street, New York, New York 10021

Department of psychiatry of Cornell University Medical College in New York City

© 1986 by the American Psychiatric Association

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Abstract

Psychiatric symptoms among patients with acquired immune deficiency syndrome (AIDS) may be functional reactions to contracting a fatal and stigmatizing disease or may be secondary to malignancies and opportunistic infections in the central nervous system (CNS). More recent evidence indicates that HTLV-III, the virus that causes AIDS, directly infects the CNS and may cause psychiatric symptoms before signs of immunodeficiency, cognitive impairment, or neurological abnormalities emerge. AIDS-related organic mental syndromes may mimic functional disorders such as chronic mild depression and acute psychosis. Both of these common presentations are illustrated with detailed case reports, and diagnostic and management guidelines are provided.

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