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Psychiatric Services, VOL. 34, No. 4

Article | April 01, 1983

Distinguishing Bipolar Disorder From Schizophrenia in Clinicai Practice: Guidelines and Case Reports

Harrison G. Pope, Jr.

Psychiatric Services 1983; doi:

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McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02178; Harvard Medical School, Boston

1983 by the American Psychiatric Association

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Abstract

Through the use of more refined diagnostic criteria and biological tests, researchers are finding that affective illness afflicts far more patients and schizophrenia far fewer patients than was formerly believed. The presence of putative "schizophrenic" symptoms is no longer held to be valuable in distinguishing between manic-de-pressive illness and schizophrenia. The author briefly reviews studies dealing with manic-de-pressive and schizophrenic symptomatology as well as tentative evidence from treatment-response studies and laboratory studies. Three case reports illustrate the tragedy of misdiagnosis.

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