0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
Intermittent Pharmacotherapy in Chronic Schizophrenia
Robert F. Prien; Roderic D. Gillis; Eugene M. Caffey, JR.
Psychiatric Services 1973; doi:
View Author and Article Information

Central Neuropsychiatric Research Laboratory Veterans Administration Hospital Perry Poin!, Maryland

Mental Health and Behavioral Sciences Service Department of Medicine and Surgery Veterans Administration Washington, D. C.

American Psychiatric Association

text A A A
PDF of the full text article.
Abstract

In an 18-hospital collaborative study, 375 chronic schizophrenics on stable maintenance doses of anti-psychotic drugs were assigned to one of four groups in which medication was withdrawn two or three days a week on varying schedules, or to one in which daily medication was continued. At the end of 16 weeks, there was no significant difference in relapse rate between the continued-treatment and intermittent-treatment groups. That finding suggests that short-term intermittent drug withdrawal is a feasible treatment policy for hospitalized chronic schizophrenics on maintenance chemotherapy. The benefits of a successful intermittent therapy program include less risk of toxicity for the patient; less work for the staff, allowing more time for other therapeutic activities; and lower drug costs for the hospital.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

+

References

+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Related Content
Books
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 1.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 22.  >
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 17.  >
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 17.  >
Textbook of Psychotherapeutic Treatments > Chapter 8.  >
Topic Collections
Psychiatric News
APA Guidelines
PubMed Articles