The book's practicality does not compromise its comprehensiveness. The introduction explains the principles of the "start low, go slow" guideline for geriatric patients and includes a helpful table of substrates, inhibitors, and inducers of five cytochrome P450 enzymes. Part 1 of the book details the four major classes of psychotropic drugs: antipsychotics, antidepressants, mood stabilizers, and anxiolytic and sedative-hypnotic medications. Each of these chapters contains not only the expected topics of indications, kinetics, interactions, side effects, and clinical use but also a section on the treatment of selected syndromes and disorders. Included are common clinical conditions among elderly persons, which are not usually covered in texts of this kind—for example, pain syndromes, sleep problems, and intoxication. Current North American medications are discussed and handily tabulated at the end of the chapter. The authors make some references to novel but unproven medication uses, which also underscore their comment that "much of current practice in geriatric prescribing is based on anecdotal evidence and case report data" and that a lot more research is needed. Nonetheless, the content is supported by robust—and again largely North American—references.