Because there is no evidence to date that any screening test accurately identifies people in the general population who are at risk of suicide, the U.S. Preventive Services Task Force and others do not recommend such screening. However, clinicians frequently encounter patients who report suicidal ideation on routinely administered questionnaires. For example, item 9 of the Patient Health Questionnaire for depression (PHQ-9) asks patients about whether and how often they have “thoughts that you would be better off dead, or of hurting yourself in some way.” A research team led by Gregory E. Simon, M.D., M.P.H., investigated whether responses to item 9 predicted a subsequent suicide attempt or suicide death. The team used electronic medical records, insurance claims, and death certificate data to document what happened to more than 84,000 outpatients age 13 and older who completed the PHQ-9 between 2007 and 2011. At Seattle’s Group Health Cooperative, where the study was conducted, patients complete the PHQ-9 at every visit for depression treatment. Even after the analyses adjusted for age, sex, treatment history, and overall depression severity, responses to item 9 of the PHQ-9 remained a strong predictor of suicide attempt (page 1195).