Although we cannot answer these questions, it is time for our field to identify what we need to know to maximize our patients’ participation in the labor market and function effectively on the job in spite of current or ongoing psychiatric difficulties. The importance of clinicians’ attention to the domain of work has been highlighted by the impact of the current economy on all working adults and particularly on those with psychiatric symptoms. Symptom reduction must be addressed, but addressing symptoms is insufficient to help patients do well occupationally. Work is intimately connected to life satisfaction, and clinicians should strengthen their ability to help patients attain positive work-related outcomes. To this end, clinicians should become more knowledgeable about their patients’ work functioning. Training programs should emphasize the importance of exploring patients’ functioning. Finally, further research is needed to test collaborative care strategies to better enable patients with psychiatric disorders to be productive and engaged in work.