A theme running through many of the chapters is that changes in prescription policy are often rancorous political issues, pitting organized medicine against various other stakeholders, such as pharmacists, consumer groups, and the FDA. For example, chapter 4, “Deciphering the Prescription,” recounts the history of efforts to require that a brief, consumer-friendly “patient package insert” (PPI) be included with all prescriptions. From our 21st century vantage point—when drug information is readily available to anyone with Internet access—we may find it odd that such a proposal could have been controversial. But the American Medical Association strenuously opposed the proposal, arguing in 1975 that this constituted excessive government regulation of medicine and that “the physician is the one who is able to ascertain the patient’s physical and emotional characteristics and whether a particular patient has need of such information.” Nonetheless, in 1980 the FDA, influenced more by consumer groups, released rules mandating PPIs for all prescription drugs. But two years later, in an illustration of the sometimes adversarial relationship between the White House and the FDA, President Ronald Reagan revoked the rule in order to trim the size of government. Thus Americans are left with the current system in which patients cobble together information from manufacturers’ PPIs and Web-based sources in order to make sense of the drugs they are taking.