This issue includes seven articles related to affective disorders, including several on bipolar disorder and several on racial and ethnic disparities in treatment for bipolar and other affective disorders. Jin H. Joo, M.D., and colleagues present their findings on the adequacy of depression treatment by primary care physicians and patient characteristics associated with receipt of inadequate care (page 1524). Mark A. Frye, M.D., and coauthors discuss patterns of diagnosis, consultation, and treatment among persons screening positive for bipolar disorder in a large U.S.-population-based study that used the Mood Disorder Questionnaire (page 1529). Joseph F. Goldberg, M.D., and coauthors discuss their study of pharmacotherapy for suicidal ideation among the first 1,000 participants in the Systemic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) (page 1534). In a related study, James M. Martinez, M.D., and associates examined predictors of serious adverse events in the same STEP-BD sample (page 1541). Amy M. Kilbourne, Ph.D., M.P.H., and associates look at whether African-American veterans are less likely to receive guideline-concordant care for bipolar disorder relative to whites (page 1549). Carl I. Cohen, M.D., and coauthors present data on racial differences in the prevalence of depression and associated factors in a sample of elderly persons (page 1556). Finally, Isabel T. Lagomasino, M.D., M.S.H.S., and associates discuss the impact of patient characteristics and source of care on disparities in the use and quality of depression treatment among 1,175 white and Latino managed primary care patients (page 1517).