Now we have growing evidence of the economic benefits of effective and appropriate psychiatric treatment. In this issue Zhang and associates demonstrate the value of treatment for depression through the relatively simple measure of lost work days. Treatment literally pays for itself; that is, employers get back what they spend for treatment. Although reduced absenteeism is often not a direct goal of treatment, it is a critical factor for any business in improving productivity and efficiency. For the depressed person, better functioning in the family, decreased morbidity from other medical conditions, and increased work productivity are other benefits of relief from the real pain and suffering of a depressive disorder. Treatment works. Every business, large and small, should take note of the value of treatment for depressive disorders.