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Article   |    
Correlates of Patterns of Substance Abuse Among Patients With Schizophrenia
Brian J. Cuffel; Kim A. Heithoff; William Lawson
Psychiatric Services 1993; doi:
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This paper was supported by grant P50-MH48197 from the National Institute of Mental Health and grant HFP48-019 from the VA Health Services Research and Development Field Program.

Institute for Mental Health Services Research, 2001 Addison Street, Suite 200, Berkeley, California 94704

University of Arkansas College of Medicine in Little Rock

University of Arkansas College of Medicine in Little Rock; Veterans Affairs Medical Center in North Little Rock

1993 by the American Psychiatric Association

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Abstract

Most previous research on substance abuse among patients with schizophrenia has not considered the types of substances abused or the confounding influences of polysubstance abuse. The authors' goals were to identify patterns of substance abuse among a sample of subjects with schizophrenia and to determine demographic and clinical correlates of these patterns. Methods: Subjects with schizophrenia were identified from the Epidemiologic Catchment Area study data base, which also provided information on the types of substances abused and on selected demographic and clinical characteristics. Latent class analysis was used to group subjects based on their patterns of substance abuse. Logistic regression was used to identify demographic and clinical correlates of the patterns. Results: Three latent classes based on patterns of substance abuse were identified: no substance abuse, abuse of alcohol and cannabis, and polysubstance abuse. Subjects with either of the two patterns of substance abuse were more likely to be younger and male and to have depressive symptoms. Conclusions: The results do not support a link between abuse of specific substances and specific clinical symptoms but do suggest a general link between substance abuse and affective disturbance among schizophrenic patients.

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