0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Articles   |    
Consumption of Antidepressants in Italy: Recent Trends and Their Significance for Public Health
Maria Rosaria Gualano, M.D.; Fabrizio Bert, M.D.; Alice Mannocci, Ph.D.; Giuseppe La Torre, M.D.; Patrizia Zeppegno, M.D.; Roberta Siliquini, M.D.
Psychiatric Services 2014; doi: 10.1176/appi.ps.201300510
View Author and Article Information

Dr. Gualano, Dr. Bert, and Prof. Siliquini are with the Department of Public Health Sciences, University of Torino, Torino, Italy (e-mail: mariarosaria.gualano@unito.it). Dr. Mannocci and Prof. La Torre are with the Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome. Prof. Zeppegno is with the Department of Translational Medicine, Institute of Psychiatry, Università del Piemonte Orientale Amedeo Avogadro, Novara, Italy.

Copyright © 2014 by the American Psychiatric Association

text A A A
PDF of the full text article.
Abstract

Objectives  The study assessed the consumption of antidepressants in Italy between 2000 and 2011 and identified trends in use.

Methods  Data on use of antidepressant drugs between 2000 and 2011 were collected from the Italian Medicines Agency database. Data were expressed as the daily defined dose (DDD) per 1,000 inhabitants. Trends in drug consumption were ascertained by logarithmic transformation of incidence rates by using the formula ln(y)=b × x, where y is the incidence rate, b is the regression coefficient, and x represents the calendar years. Time trends were expressed as expected annual percentage change (EAPC). A significance level of .05 was chosen.

Results  Antidepressant consumption increased drastically between 2000 and 2011, from 8.18 to 36.12 DDD per 1,000 inhabitants per day. A single joinpoint (time point with a significant trend change) occurred in 2002 (EAPC=56.4%, 2000–2002, and 6.2%, 2002–2011). The trend analysis stratified by type of drug showed a huge increase in consumption of selective serotonin reuptake inhibitors and other antidepressants and a decrease in consumption of tricyclic antidepressants.

Conclusions  Mental disorders are less stigmatized now than in the past. In Italy and elsewhere, antidepressant use is growing, and it would be important to monitor this trend, especially considering the possible effects of the current economic crisis on mental health. In this scenario, the role of public health in mental health promotion has become fundamental.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

+

References

+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Related Content
Articles
Books
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 34.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 57.  >
The American Psychiatric Publishing Textbook of Substance Abuse Treatment, 4th Edition > Chapter 39.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 62.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 62.  >
Topic Collections
Psychiatric News
APA Guidelines
PubMed Articles
Sertraline versus other antidepressive agents for depression. Cochrane Database Syst Rev 2010;(1):CD006117.
Sertraline versus other antidepressive agents for depression. Cochrane Database Syst Rev 2010;(4):CD006117.