In Reply: Dr. Kennedy and Dr. Aas bemoan the loss of axis V in DSM-5, stating that its “genius . . . has been its focus on global measures of functioning within diagnoses and across all diagnoses to assess outcome of treatment.” They list certain instruments, including the GAF, the Mental Illness, Research, Education and Clinical Center GAF (MIRECC GAF), the Social and Occupational Functioning Assessment Scale, and the Kennedy Axis V, all with similar anchor points, rating instructions, and scoring continua, as preferable to those offered in Section III of DSM-5. We believe that they overstate the advantages of clinician-rated global scales and minimize the advantages of the DSM-5 measures.