Suicide rates increase among middle-aged U.S. adults: A report by the Centers for Disease Control and Prevention (CDC) underscores the need to direct suicide prevention efforts, which have traditionally targeted youths and elderly persons, toward middle-aged Americans. The CDC analysis found an increase of 28.4% between 1999 and 2010 in the annual, age-adjusted suicide rate among middle-aged adults (age 35–64), from 13.7 per 100,000 population in 1999 to 17.6 in 2010. Rates among both men and women in this age group increased substantially. The greatest increases were among American Indian–Alaska Natives (65.2%, from 11.2 to 18.5 per 100,000) and whites (40.4%, from 15.9 to 22.3). The three most common mechanisms were firearms, poisoning (predominantly drug overdose), and suffocation (predominantly hanging), and the greatest increase was observed for suffocation (81.3%, from 2.3 to 4.1), followed by poisoning (24.4%, from 3.0 to 3.8) and firearms (14.4%, from 7.2 to 8.3). The report was published in the May 3 issue of Morbidity and Mortality Weekly Report (www.cdc.gov/mmwr/preview/mmwrhtml/mm6217a1.htm?s_cid=mm6217a1_w).