New guidelines to manage childhood aggression: Researchers from the Mayo Clinic in collaboration with researchers from other institutions and experts on youth mental health have developed new guidelines for primary care providers and mental health practitioners to manage the common but often complex problem of childhood aggression. Goals include improving diagnosis and care and avoiding inappropriate use of medication. Peter Jensen, M.D., a Mayo Clinic psychiatrist who led the development of the new guidelines, noted that antipsychotics and mood-stabilizing drugs are increasingly prescribed to children to treat overt aggression. “These large-scale shifts in treatment practices have occurred despite potentially troubling side effects and a lack of supportive empirical evidence,” Jensen said. Recommendations include carefully engaging in and forming a strong treatment alliance with the patient and family; conducting a rigorous, thorough diagnostic workup; carefully measuring treatment response and outcomes by using reliable assessment tools; providing education and support for families; helping families obtain community and educational resources; using proven psychologicaltherapies before starting any antipsychotic or mood-stabilizing medications; and carefully tracking (and preventing, whenever possible) side effects. Guideline development was funded by the Agency for Healthcare Research and Quality, the Annie E. Casey Foundation, the REACH Institute, and the states of New York, Texas, and California. The guidelines, “Treatment of Maladaptive Aggression in Youth,” which were published online in the journal Pediatrics, are free and publicly available via a downloadable, user-friendly toolkit (www.thereachinstitute.org/files/documents/t-may-final.pdf).