Wills' focus is on the drugs themselves, including their chemistry, pharmacology, nomenclature, history, psychological effects, and toxicity. The book is organized into chapters that discuss a specific drug, such as LSD, or a class of drugs, such as opioids. Topics such as the adverse effects of IV drug injection, the use of drugs in the medically ill, and drugs in pregnancy and breast feeding are covered in separate chapters. The information is presented clearly, and it is detailed enough to answer the needs of virtually all practitioners other than specialists. The clinical literature is liberally and appropriately cited, which helps to establish a tone of authority on the subject matter, as well as to direct the reader toward pertinent articles.